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Some individuals notice improved sleep quality, reduced morning stiffness, or slightly better tolerance for activities that previously caused discomfort

This leads to severe oxidative stress, lipid peroxidation, and catastrophic damage to cellular membranes and mitochondrial DNA, triggering systemic inflammation

Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract

Long-term acetyl-L-carnitine treatment in Alzheimer's disease

When we used succinic acid instead of fumaric acid as the substrate of Cp1A, 3-NPH- t -ES and 3-NPH-fumaric acid were produced, albeit with lower efficiency (Extended Data Fig