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The crystal structure of the human enzyme cocrystallized with glutamate showed that the -carboxylate of the -glutamyl moiety of the substrate is stabilized within the active site of the enzyme by forming hydrogen bonds with Arg-107, Ser 451, and Ser-452S (West et al., 2013b)

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(More information) There are insufficient data to suggest a link between vitamin C status and the risk of developing a given type of cancer