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In accordance with previous studies 28,29 , we administered a ferroptosis inducer, erastin, to HT1080 cell culture and observed decrease in GSH levels by flow cytometry of RT signals (Fig

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Apoptosis of uterine leiomyoma cells was also stimulated by the expression of caspase-3, an important mediator for apoptosis, and by caspase-9, an initiator of apoptosis (Malik et al., 2009)

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It works upstream in the hormone cascade, offering a physiologic and highly controlled way to enhance hormone levels