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YTHDF1 knockdown significantly down-regulated cytochrome C, while up-regulating Ferritin, TFAM and GPX4 (Fig

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities