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A damaged skin barrier can perpetuate inflammation and oxidative stress, both of which trigger increased melanin production as a protective response

The researchers successfully used the peptide to decrease levels of chromosome aberrations in the mice, observing that treatment with melatonin had no such effect [4]

Products That May Help Prescription products such as retinoids (derivatives of vitamin A

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Women who may become pregnant should take a supplement with folic acid to prevent serious birth defects

Acknowledgments We thank Molly Thompson for preparing the figures