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On the left, the riboflavin-dependent enzyme glutathione reductase converts oxidized glutathione (GSSG) into two molecules of reduced glutathione (GSH)
Among the polyphenol class are flavonoids, which include quercetin and luteolin, both showing antioxidant and anti-inflammatory properties [91,92]
Additionally, it has been demonstrated that also chronic hepatitis C virus (HCV) infection in hepatocyte cell lines led to a decreased levels of reduced GSH and a concomitant increase of oxidative stress ( The altered intracellular redox state has been envisaged as target for anti-influenza therapy, but also in this case the data arising from in vivo studies are inconsistent, and in some cases have indicated that antioxidants could exacerbate the disease
[DOI] [PubMed] [Google Scholar] 239.Jiang X., Liu Y., Ma L., et al
When a quality issue is identified post-distribution, the lot number is the mechanism for targeted recall only the affected batch is pulled, not the entire product line
