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92 Resveratrol also inhibits circulating oncogenic microRNAs (miRs) such as miR-19, miR-21, and miR-30a-5p, thereby suppressing the expression of genes that code for epidermal growth factor receptor, signal transducer and activator of transcription, COX-2, and downregulating the mTOR signaling pathway

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More importantly, this reaction occurs spontaneously in the inner mitochondrial membrane (complexes I to V) via electron transport chain reactions, where free electrons react with oxygen molecules

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