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Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

145,146,147 Research involving mice lacking OGG1 validated its ability to eliminate 8-oxoguanine (8oxoG) damage

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Taken together, we have demonstrated that NAC may ameliorate oxidative stress and neuroinflammatory impairments induced by chronic ethanol exposure in APP/PS1 mice

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doi:10.1210/jc.2017-01739 Panchaud A, Rousson V, Vial T, et al