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However, these injections can sometimes lead to various side effects, ranging from mild to severe

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

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These body composition changes occurred without any measured change in food intake meaning the weight loss was driven by metabolic changes rather than appetite suppression

The energy increase was noticeable at the first shot

Note: Same-product quantities only