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Natural products as pharmacological modulators of mitochondrial dysfunctions for the treatments of alzheimer's disease: A comprehensive review

The tegumental and subtegumental regions of these NTS showed alterations including disruption of tegument, extensive lysis of subtegumental regions with presence of numerous and vacuoles with diverse sizes, and loss of the basal membrane

Most evidence comes from animal models and in vitro studies

Despite considerable progress in our understanding of MASH, the particular mechanisms underlying disease development and the variable progression among patients with similar clinical risk factors remain inadequately explained

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