DONT use the nasal spray within 1 hour of using other nasal decongestants or allergy sprays, as this can wash the medicine away before it absorbs
Its potential is in a real biological effect involving tissue repair, control of inflammation, development of blood vessels, as well as in a general positive safety profile observed in animal studies and off-label use
These include: Nausea (affecting up to 1 in 5 patients) usually most pronounced during dose escalation and often improves over time Diarrhoea may be mild to moderate and typically transient Vomiting less common than nausea but can occur, particularly in the first few weeks Constipation resulting from slowed gastric emptying Abdominal pain and bloating often related to delayed gastric emptying Reduced appetite this is an intended therapeutic effect but can be pronounced The frequency of these side effects tends to be dose-dependent, with higher rates at higher doses
2022;82(9):1643-1659.e10
Molecules (Basel, Switzerland) 25(3):609
However, the IM route was the top-ranked statistically, followed by the SL and then the oral routes, but without clinical significance
