Rolipram, a phosphodiesterase-4 inhibitor, indirectly enhances proteasome activity by increasing cAMP levels and reduces tau aggregation in AD models
Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE
Lonza), cells were maintained in a humidified environment at 37C under a 5% CO2 atmosphere for 48 h
Cancer Immunol
To determine whether ETV6 accumulation contributes to EC tumorigenesis driven by FBXW7 deficiency, we generated FBXW7 KO Ishikawa and HEC-1A cells and subsequently depleted ETV6 using shRNA-mediated knockdown (Fig
In mammals, the mechanism facilitates the transfer of sulfur from homocysteine to cysteine through cystathionine (Figure 1)