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Patients had undergone laparoscopic sleeve gastrectomy before starting semaglutide

Scientific Reports , 11 (1)

The Asp9 forms a hydrogen bond with Arg370, while Ser8 and Ser11 of Tirzepatide form a network of hydrogen bonds involving the receptor residue Glu288, Arg 289, and Asn290

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This deficiency can also be prevalent in heavy smokers and drinkers