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For example, type 2 diabetes has well-documented mitochondrial oxidative stress, accompanied by depleted or oxidized GSH levels

In both 1-methyl-4-phenylpyridinium (MPP + )-exposed SH-SY5Y cells and MPTP-administered mice, Nrf2 activation regulates the upregulation of brain-derived neurotrophic factor (BDNF) transcription, thereby ameliorating dopaminergic neurotoxicity (171)

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Zhang Y, Cao KX, Niu QJ, Deng J, Zhao L, Khalil MM, et al

The experiment was carried out between 11.00 and 12.00 h at light-saturating intensity, 2 cm 2 of leaf area, block temperature (25 C), CO 2 flow controller (300 mol s 1 ) and PAR (1600 mol photons m 2 s 1 )

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