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Additionally, Nrf2 , activated by oxidative stress, enhances NOS3 transcription by upregulating antioxidant response elements in the NOS3 promoter (Wu et al., 2019)

Standard laboratory practice also includes allowing refrigerated vials to reach room temperature before reconstitution to minimise condensation inside the vial

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Additional files Additional file 1: (download TIF Figure S1

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Stress, chronic illness, and breastfeeding are also common reasons for delayed or missed periods, as they can impact hormonal balance and reproductive health