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Studies on bovine oocyte maturation and embryo development found that telomerase activation via Epithalon significantly improved oocyte maturation rates and enhanced post-thawed embryo quality, with increased blastocyst hatching rates and improved implantation potential

This suggests that BPA may inhibit the proliferation of granulosa cells

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Genetic susceptibility plays a foundational role, with shared polymorphisms and risk locisuch as MALAT1, ALDH2, and JMJD3implicated in both vascular and oncogenic pathways