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Other tested genes encode fructose-1,6-bisphosphate aldolase ( FBPaldolase ), which catalyze the conversion of two triose-3-phosphates into FBP

One honest caveat from the data: because the Phase 2 curve had not clearly plateaued by the end of the study, the full ceiling of the effect is genuinely not yet known that is one of the questions the Phase 3 TRIUMPH program is designed to answer

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Because biological APIs are inherently labile, these stresses and environmental transitions introduce the risk of conformational change, aggregation between API molecules or API and excipient(s), and precipitation

doi: 10.1016/j.prp.2024.155596 72 FeiYCaoDLiYWangZDongRZhuMet al

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