In a recent review (2018) by the famous Cochrane Institute, it was reported that studies which had been published on this topic only provided very low-quality evidence that oral B12 is as efficacious as intramuscular B12
For weight loss specifically, this is not a close comparison
Vitamin B Complex Injections can be administered in older patients also but caution is needed
The drugs may interact with certain food items or with health conditions
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Factors such as convenience, cost savings, potential digestive absorption issues, and comfort with self-administering injections can influence patients preferences