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GSH and glucose measurements for each diabetic patient at 0, 4 and 8 weeks, together with a control value from non-diabetic subjects, were fit to the model

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Concurrently, the accumulation of peroxidation products activates the Ras/Raf/MEK/ERK pathway in endometrial cells, upregulating matrix metalloproteinase (MMP-2/MMP-9) expression and causing excessive degradation of the extracellular matrix (ECM)