Fuhrmann found that the content of NCOA4 in macrophages decreased under hypoxic conditions, increasing intracellular ferritin content, and thereby enhancing macrophage resistance to ferroptosis [69]
Cons: Marketing often implies benefits that arent directly proven
Overall, this is a well-studied and low-irritation brightener that's a great pick for anyone dealing with uneven skin tone
With dozens of positive human clinical studies with beetroot, there is some evidence for dosage levels needed to improve cardiovascular health, physical strength and tolerance, and recovery from exercise using beetroot powder
Briggs JP, Skott O, Schnermann J (1990) Cellular mechanisms within the juxtaglomerular apparatus
Inter-individual Variation in Hepatic Drug Metabolism