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Gould, Pharmacol

Another mitochondria localized member of the folate metabolizing enzymes is methylene tetrahydrofolate dehydrogenase (NADP + dependent) 1-like which is encoded by the MTHFD1L gene

doi: 10.1111/pce.13602 28 HanY.ChaouchS.MhamdiA.QuevalG.ZechmannB.NoctorG

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USDA National Nutrient Database for Standard Reference Release 28

The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory