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The RSL3-induced reduction in cell viability based on the PrestoBlue or APH assay could be fully rescued by the supplementation with FER1 (DMSO-soluble) or the broad radical scavenger TEMPO (water-soluble) (Fig

Cellular and Molecular Neurobiology, 18(3), 299310

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Typically, before a drug can be marketed, it must pass through a series of clinical trials, in order to identify safe dosages and to determine that any positive outcomes are due to the substance itself, and not to bias in the study design

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