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doi: 10.1038/352168a0

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By using Western blot, immunofluorescence and other techniques, the expression and distribution of tight junction proteins were analyzed, and the effect of IGF-1 LR3 on barrier integrity was studied

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Allopurinol: the most commonly used first-line agent, which inhibits uric acid production

An earlier and arguably more influential paper from three Indian dermatologists, published in the Indian Journal of Dermatology, Venereology and Leprology , identified three randomised controlled trials supporting a skin-lightening effect and a good safety profile for topical and oral glutathione specifically