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When NNMT is overactive, it consumes S-adenosylmethionine (SAM) and reduces levels of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme involved in cellular energy production

This means healthcare providers can help patients with vitamin B12 deficiency get better by using proven methods (PMC11128391)

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Vitamin B12: another water-soluble vitamin that is easily absorbed by the body and plays a role in metabolism processes [3]

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Vitamin B12 Injections vs Supplements: The Key Differences The main difference lies in how each method delivers B12 into your body