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However, MenSCs display a significantly faster proliferation rate, with a population doubling time of approximately 19.4 hoursroughly twice as fast as that of bone marrow-derived MSCs (BM-MSCs) (Skliut et al., 2021)

Exercise-Induced Oxidative Stress Intense or prolonged exercise generates substantial oxidative stress through increased oxygen consumption and metabolic rate, increased mitochondrial electron leakage producing reactive oxygen species, recruitment of inflammatory immune cells to exercising muscles, and mechanical stress on tissues producing oxidative damage

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Nanoscale 5 , 1262412632, (2013)

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Such hyper-inflammatory state could lead to loss of appetite, altered intestinal absorption, impaired gut permeability, and malnutrition 683,684