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This applies especially when using it for injections or medication preparation

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[6] [8] Estradiol cypionate is contraindicated during pregnancy because exogenous estrogen has no therapeutic role in gestation and in utero exposure could theoretically disturb fetal endocrine development or contribute to structural anomalies, although robust human teratogenicity data are limited

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However, we recommend refrigerating them as soon as possible upon arrival to ensure proper storage and extend their longevity