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elegans , and mammalian cells resulted in increased mitochondrial function and biogenesis, UPR mt , and antioxidant response gene expression 108,109,110

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Unfortunately, the response rates remain relatively low

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Whereafter, L-theanine could regulate the innate immunity of mice with immune stress induced by ETEC, mainly by inhibiting the overexpression of nucleotide-binding oligomerization domain, IL-1, and TNF-, partially reducing the protein level of NF-B p65, and suppressing the phosphorylation of ERK1/2 (96)

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