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Strong dual inducers (rifampin, carbamazepine, phenytoin) decrease apixaban exposure by approximately 54% and should be avoided [1]

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Sikiric, P., Udovicic, M., Barisic, I., Balenovic, D., Zivanovic Posilovic, G., Strinic, D., Uzun, S., Sikiric, S., Krezic, I., Zizek, H., Yago, H., Gojkovic, S., Smoday, I

Understanding the correct dosing of these peptides is crucial

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This is particularly important in individuals who are unable to absorb vitamin B12 from the gastrointestinal tract due to conditions such as pernicious anemia, atrophic gastritis, or after certain surgeries