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Placebo-controlled pilot trial of mecamylamine for treatment of autism spectrum disorders

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This finding is particularly noteworthy given that some trials extended to 24 weeks of continuous exposure and included participants with obesity-related comorbidities who might be expected to have higher baseline health risks

Short-bowel rats habitually presented with liver lesions (Figs 4and 10) as well as increased serum values of ALT, AST, and particularly bilirubin (Fig 5), which were all markedly exacer- bated in rats administered diclofenac, and even more so in rats coadministered diclofenac and L-NAME (Figs 5and 9)

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