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In high-risk patients, use semaglutide with caution

That's exactly the purpose of working with a licensed healthcare provider, not just buying vitamin supplements at the grocery store

Most patients see measurable reduction in stubborn fat, particularly central and visceral fat, over a 6-12 week cycle

Current dose is 0.5 mg weekly after 4 weeks at 0.25 mg

Although FOXO4s specific effects on mitochondria are as direct as the other peptides above, it is known to regulate the expression of genes involved in oxidative stress response and energy metabolism, which can impact mitochondrial function indirectly (Liu, 2019)