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Visceral fat exhibits higher metabolic activity, greater innervation, richer blood supply, and importantly, higher concentrations of beta-3 adrenergic receptors compared to most subcutaneous depots

One proposed mechanism is that lactate enhances hippocampal neuronal firing, potentially contributing to panic symptoms ( Holdemanella has been associated with reduced right amygdala and hippocampal volumes (Wanapaisan et al., 2022) brain regions consistently reduced in PTSD individuals ( Additional population studies have expanded these findings

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