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Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death

As reactive aldehydes are known to form DNA adducts and to induce DNA damage [67,68], we performed immunohistochemistry for -H2AX on the liver sections

Conjugation to xenobiotics - In some instances, depending on the state of the xenobiotic, Glutathione joins with it instead of metabolizing it

Vitamin B12 Benefits Vitamin B12 is necessary for proper red blood cell production, DNA formation, nerve function, and metabolism

Ji and Leeuwenburgh 1995)