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Corvaro M

The metabolic syndrome is in fact a group of risk factors which are listed as insulin resistance or glucose intolerance, abdominal/visceral obesity, dyslipidemia (high triglycerides, low HDL-C, high LDL-C), elevated blood pressure, prothrombotic state ( high fibrinogen or PAI-1) and proinflammatory state (elevated CRP, TNF- , IL-6)

All individuals with these atypical variants exhibited skin hyperextensibility as seen in individuals with classical EDS and classical-like EDS and evidence of tissue fragility as seen in individuals with vEDS

Intensive nourishment for the skin

Regarding the recent developments concerning the Wnt/-catenin pathway, the importance of the pathway in understanding different diseases is becoming the future direction for therapeutic research