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Increased expression levels of genes associated with autophagy, oxidative stress and inflammation were observed in copper-treated HepG2 ATP7B-KO cells and in primary hepatocytes from patients with WD

The animals were restrained with their heads positioned downward and abdomens upward for the i.p

doi: 10.1111/hdi.12414 76 KandpalM.IndariO.BaralB.JakhmolaS.TiwariD.BhandariV.et al

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This administration route not only optimises the peptides absorption but also simplifies the experimental process, providing a direct pathway to systemic circulation