Disclosure: All opinions remain the writers own
Research suggests DSIP plays a role in modulating neurotransmitter activity, stress hormones, and neuroendocrine pathways
In cardiovascular diseases, elabela antagonizes angiotensin II-mediated negative changes in heart structure, heart dysfunction, and myocardial fibrosis by inhibiting the IL-6/STAT3/GPX4 pathway [91]
The mechanism by which this binding is induced is still emerging, but likely includes contributions from the repressor of Nrf2, Keap1, heterodimeric binding partners, and ubiquitin/proteasome-mediated regulation of Nrf2 half-life 4 , 6 , 7 , 8 , 9 , 10
January 2026
Lack of Direct Evidence : Because comprehensive clinical trials on this specific combination are lacking, much of what we know is based on limited studies and anecdotal reports