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13,14 In contrast, although our study showed that patients who had immune-related adverse events received a significantly higher median number of checkpoint inhibitor doses compared with patients without such adverse events, the number of checkpoint inhibitor doses received did not significantly predict the occurrence of immune-related adverse events

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Alpha-lipoic is a naturally occurring compound that may help the body from oxidative damage

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This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells