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The inhibition of serine and glycine bidirectional conversion by sertraline prior irradiation reduces the pool of nucleotides, as we previously observed, and concurrent and post-treatment with sertraline might hinder the synthesis of the antioxidant GSH and NADPH production, which exposes cancer cells to the accumulation of endogenous ROS and radiation-induced ROS causing severe oxidative stress [70]
Another early investigation published in the European Journal of Endocrinology documented that, unlike older GH-releasing peptides, such as GHRP-2 or GHRP-6, ipamorelins GH stimulation is highly selective and does not significantly increase cortisol or prolactin levels, suggesting a cleaner hormonal profile with fewer off-target endocrine effects compared to earlier secretagogues
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Plant metal interaction: Elsevier
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