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Intracellular GSH is compartmentalized within the nucleus, mitochondria and endoplasmic reticulum, all of which constitute separate redox pools that are distinct from the cytoplasmic pool in terms of distribution of the GSH and GSSG forms, their redox potential and their control of cellular activities

For example, the pancreas produces fewer hormones, leading to diabetes, fatty liver, obesity, and other problems

Long COVID and ME/CFS are linked to severe oxidative stress and impaired natural detoxification pathways

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And so the heart disease mortality basically by the end of the trial was just kind of flat

Brain Res 2009