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Simultaneously, the assembly and activation of the NLRP3 (nucleotide-binding domain-like receptor family pyrin domain containing-3) inflammasome complex, regulated by NF-kB, are enhanced in neurons, microglia, and astrocytes within the trigeminal ganglia, trigeminal nucleus caudalis, and cortical areas (9, 10, 39, 47)

These enzymes constitute the first line of cellular defense against reactive oxygen species (ROS) and oxidative damage to cellular macromolecules

Regulatory mechanisms of heme regulatory protein BACH1: A potential therapeutic target for cancer