Future work should focus on the degradation of glutathione using ChaC and PepD, and if this can be detected using out biosensor
Fiscal year Facility Registrations 2016 1,425 2017 1,442 2018 1,269 2019 1,286 2020 1,300 2021 1,340 2022 1,385 2023 1,394 2024 1,447 2025 1,397 Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available)India continues to lead with 396 facilities, US and China follow India maintains its dominance in total facility registrations with the FDA, registering 396 facilities for FY2025
Animal studies For the nephrotoxicity study, mice were randomly housed (as shipped) in four individually ventilated cages (25 mice/cage) with free access to food and water
The intestinal wall contains CYP450 enzymes, particularly CYP3A4, which begin metabolising some drugs even before they're absorbed, contributing to first-pass effects
Hendrickse RG, Coulter JB, Lamplugh SM et al (1982) Aflatoxins and kwashiorkor: a study in Sudanese children
doi:10.3390/pathogens14010090 8
