It is often the dose, timing, and stacking
Comparison between Serum Holotranscobalamin and Total Vitamin B12 as Indicators of Vitamin B12 Status
JqL, QL, QZ, and JnL wrote the manuscript

Description Ingredients: Purified water, butylene glycol, beeswax, caprylic/capric triglyceride, niacinamide, cetearyl alcohol, isononyl isononanoate, arachidyl alcohol, 1,2-hexanediol, polyglyceryl-3 methylglucose distearate, behenyl alcohol, glyceryl stearate, betaine, arachidyl glucoside, allantoin, sorbitan oleate, panthenol, hydrogenated lecithin, tocopherol, xanthan gum, glycerin, Glutathione (600 ppm), ethylhexylglycerin, dipotassium glycyrrhizate, stearic acid, disodium EDTA, bisabolol, sodium hyaluronate, ascorbyl tetraisopalmitate, glucose, balm leaf extract, ladys mantle extract, yarrow extract, speedwell extract, peppermint leaf extract, evening primrose extract, polyglyceryl-10 stearate, ceramide NP, sodium ascorbyl phosphate, ceramide NS, cholesterol, phytosphingosine, ceramide AP, ceramide AS, sodium hydroxide, biotin, acetyl hexapeptide-8, copper tripeptide-1, pyridoxine, oligopeptide-29, oligopeptide-32, cyanocobalamine, palmitoyl pentapeptide-4, ceramide EP, riboflavin, beta-carotene, thiamine HCL, fragrance.

Human antimicrobial peptide LL-37 induces glial-mediated neuroinflammation
P.RangelM.et al (2023)