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While the specific search TB-500 returns limited PubMed results, thymosin beta-4 itself has 167+ studies in wound healing research alone, plus hundreds more across other domains

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Neurotransmitter system interactions: Published research has examined interactions with dopaminergic, serotonergic, and GABAergic systems in animal models, contributing to its use in neurobiological research contexts

It also delays the emptying of your stomach, which helps you feel fuller for longer

DOI: 10.1007/s11095-009-0045-6 DailyMed

Its also not clear that mega-doses of B vitamins are safe over the long haul, especially in certain populations