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Furthermore, in line with the beneficial effects of RAS blockers, researchers have also shown that the administration of empagliflozin, a SGLT2i, reduced the expression of IL-6, CCL2, and NF-B in the kidneys of diabetic Akita mice, as well as in cultured kidney tubular cells exposed to high glucose (152, 159)

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DIA MS2 scans were acquired in the Astral mass analyser with a 3 ms maximum injection time using a variable windowing scheme, using 2 Da windows from 380 to 680 m/z , 4 Da windows from 680 to 800 m/z and 8 Da windows from 800 to 980 m/z

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