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2.5.2 JAK/STAT modulators JAK/STAT signaling, particularly STAT3, plays a major role in Th17 cell differentiation and keratinocyte proliferation

Full results typically become apparent after several weeks of consistent treatment

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This type of interaction has been described mostly for metabolic reactions involving CYP2E1, but it also may involve CYP3A4 and CYP1A2 (Salmela et al

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