An important implication of these findings is that any particular plant extract/botanical preparation with specific qualitative characteristics, quantitative composition, and the product-specific HPLC fingerprint can exhibit quite different pharmacological activity and pharmaceutical profile (signature) depending on the dose, often exhibiting a dual response in the organism from positive to inactive or even harmful
The degree of efficacy was judged by examining treatment effects on pulmonary edema formation (PEF) as measured by wet/dry weight (WW/DW) ratios, real-time (in situ) lung weight gain (LWG), survival rates (SR), odds ratios, and glutathione (GSH) redox states
magna in test solutions of different pH
These results illustrate that the low compliance to the ketogenic diet and variable efficacy of mTOR-targeting drugs mean that some patients have a low rate of seizure cessation, and the targeted effect of decanoic acid may be in reducing mTOR activity
Key finding: AOD 9604 reduced visceral fat by 38%, improved HOMA-IR by 52%, and corrected glucose intolerance (fasting glucose -28%)
Parkinsonism Relat D (2018) 55:1227
