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Moreover, the rate at which telomeres shorten is accelerated by inflammation, oxidative stress, nutritional deficiencies, genetic predisposition, and other lifestyle habits such as smoking, recreational drug use, alcohol use and exposure to toxic chemicals and moulds

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A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome

If you notice persistent discomfort, you may want to lower your dose and slowly work your way up

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10.1186/s12915-014-0056-6 BMC Biol