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Methods for the analysis of vitamin B 12 in food Several methods have been used to determine the vitamin B 12 content in foods including microbiological assays, chemiluminescence assays, polarographic, spectrophotometric, and high-performance liquid chromatography processes
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For example, a vegan woman who hadnt been taking B12 developed a deficiency and had to be treated with such high doses of the vitamin that her face erupted in acne, as you can see at 4:49 in my video
Cutaneous signs of nutritional disorders