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There may be a threshold at which the neuroprotective functions of reactive astrocytes shift toward neurotoxic effects, acting as adversaries of neurons

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Therapeutic interventions for diabetes mellitus-associated complications

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Conkright, M

Several studies have found that cadmium can promote ferroptosis through ERS-mediated activation of autophagy, revealing a potential mechanism for ferroptosis activation by the ERS/autophagy axis [93, 94]