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MAPK (Table 1) comprises three families: the extracellular signal-regulated kinases (ERK), the other family stress-activated protein kinases (SAPKs) have two members, first c-Jun N terminal kinase (JNK) and p38 [36]

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Fedoriw, A., Shi, L., OBrien, S., Smitheman, K

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These differences underscore that semaglutide is not simply replacement of a deficient hormone but rather pharmacological augmentation of GLP-1 receptor signaling for therapeutic benefit

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