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reduced glutathione (GSH) is the active form that is able to repair oxidative damage, and oxidized glutathione (GSSG) is the inactive form that can be recycled back into GSH

First of all, ferroptosis may be impacted by the overexpression of genes related to iron metabolism, such as HO-1, caused by the activation of HIF-1 in hypoxic environments ( Figure 3 )

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